Guangzhou Kafen Biotech Co.,Ltd
|Place of Origin:||China|
|Minimum Order Quantity:||10g|
|Packaging Details:||As your request|
|Delivery Time:||Within 24 hours after receiving your payment|
|Payment Terms:||T/T, Western Union, MoneyGram,Bitcoin|
Nootropics Raw Material Powder Antidepressant Coluracetam for Smart Brain Improvemrnt CAS:135463-81-9
Storage Temp.: 2-8°C
Appearance: white crystals
Usage: Brain health drug;Nootropic
|ANALYTICAL ITEMS||SPECIFICATION||ANALYTICAL RESULTS|
|Appearance||White to Off-White Powder||White powder|
|Related substances||A single impurity≤0.5%||0.13%|
|Loss on drying||≤0.5%||0.09%|
|Conclusion||Confirms to Enterprise Standard|
Coluracetam is one of the newer racetam nootropics to hit the market. The idea behind this powerful compound is that it acts as a Choline uptake enhancer. In other words, the purpose of this nootropic is to enhance the effects of Choline on the brain and body. This includes the increased production of Acetylcholine, without which it would be impossible move our muscles or even be able to remember simple facts. Not only does coluracetam increase the production of Acetylcholine, but it also speeds up its flow in brain synapses
Rat studies have shown that Coluracetam is helpful in reducing the effects of learning deficits. Not only did it reduce these effects, but it also did not have any of the normally expected side effects . This product is also considered to have great potential as a casual mood enhancer and a powerful memory booster. There is even evidence to suggest that the positive effects on the brain are semi-permanent . Users also report a rather wide range of Coluracetam benefits. This includes enhanced concentration and speed of cognition. Coluracetam also helps with both short and medium term memory. There are also a number of reports of being able to study and focus more easily while taking this nootropic.
Coluracetam enhances high-affinity choline uptake (HACU) which is the rate-limiting step of acetylcholine (ACh) synthesis, and is the only known choline uptake enhancer to currently exist. Studies have shown Coluracetam to improve learning impairment on a single oral dose given to rats which have been exposed to cholinergic neurotoxins. Subsequent studies have shown that it may induce long-lasting procognitive effects by changing the choline transporter regulation system.
Depression and Anxiety
BrainCells Inc, found that a dosage of 240mg (split into three daily doses of 80mg) was useful in treating major depression co-morbid with GAD (generalized anxiety disorder). However, the differences were most pronounced in those who didn't find relief in using standard antidepressants. After one dose, there were no noticeable differences, but after 2 doses at 80mg, 36% had improved scores during a depression assessment test.
Coluracetam has been associated with optic benefits such as enhanced color vision, recognition and vividness. Although there isn't any conclusive evidence to support the mechanisms behind this benefit, experts believe that Coluracetam works in the part of the brain that runs visual processes.
Since the study subjects were rats, there aren't any recommended human dosages, but there is a general guideline for conversion.
In rats, the dosage ranged between 1 mg/kg and 10 mg/kg per day. By using allometric scaling, the dose becomes 2.9 mg/kg in humans, so the average dose should not exceed 203.5 mg daily for someone in a typical weight class.
There isn't information to indicate toxicity of Coluracetam, although doses given at the above increments showed no negative side effects. If you haven't used a nootropic before, you may develop headache after use, which is a common in first time users. By stacking the Coluracetam with Choline, you'll reduce this risk.
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