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BP / USP Grade Vetoryl Trilostane Steroids Treatment Cushing Syndrome CAS 13647-35-3

BP / USP Grade Vetoryl Trilostane Steroids Treatment Cushing Syndrome CAS 13647-35-3

    • BP / USP Grade Vetoryl Trilostane Steroids Treatment Cushing Syndrome CAS 13647-35-3
    • BP / USP Grade Vetoryl Trilostane Steroids Treatment Cushing Syndrome CAS 13647-35-3
    • BP / USP Grade Vetoryl Trilostane Steroids Treatment Cushing Syndrome CAS 13647-35-3
    • BP / USP Grade Vetoryl Trilostane Steroids Treatment Cushing Syndrome CAS 13647-35-3
  • BP / USP Grade Vetoryl Trilostane Steroids Treatment Cushing Syndrome CAS 13647-35-3

    Product Details:

    Place of Origin: Guangdong
    Brand Name: Kafen
    Certification: USP, GMP ,ISO9001, UKAS,BP
    Model Number: 13647-35-3

    Payment & Shipping Terms:

    Minimum Order Quantity: 10g
    Price: negotiable
    Packaging Details: Disguised and discreet or according to every customer's requirements
    Delivery Time: within 8 hours after receiving your payment
    Payment Terms: D/A, L/C, D/P, T/T, Western Union, MoneyGram, Bitcoin
    Supply Ability: 5000kg/month
    Contact Now
    Detailed Product Description
    CAS: 13647-35-3 MF: C20H27NO3
    MW: 329.4333 Appearance: White Powder
    Storage: Keep In Dry And Avoid Light, Heat And Moisture Suitable For: Adult Or Bodybuilders
    Assay: 99% Package: Disguised And Discreet Or According To Every Customer's Requirements

     

    BP / USP Grade Vetoryl Trilostane Steroids Treatment Cushing Syndrome


    1. Quick Details:


    Product Name:Trilostane
    Synonym: Vetoryl
    CAS :13647-35-3
    Molecular Formula:C20H27NO3
    Molecular Weight:329.4333
    Assay :99%
    Grade : Pharmaceutical Grade
    Storage: Shading, confined preservation
    Appearance: White crystalline powder
    Usage : Trilostane can inhibit cortical hormone in the process of synthesis of 3 beta dehydrogenase, make the cortisol, aldosterone synthesis decreased, clinically used in the treatment of Cushing syndrome (hypercortisolism) and primary aldosteronism. This product also had significantly effect to decreased serum testosterone level.

     

     

     

    2 . Description:

     

    Trilostane blocks an enzyme involved in the production of several steroids including cortisol. Inhibiting this enzyme inhibits the production of cortisol. In Cushing's syndrome, the adrenal gland overproduces steroids. Although steroids are important for various functions of the body, too much can cause problems. Trilostane reduces the amount of steroids produced by the adrenal gland.

    Trilostane A drug that interferes with the natural synthesis of steroids and is used to treat breast cancer in post-menopausal women. A brand name is Modrenal.

    A short-acting adrenocortical suppressant for oral use in dogs. Trilostane blocks the adrenal gland from making too many steroids. Although steroids are important for various functions of the body, too much can cause problems.

     

     

     

    3 . Function:

     

    Trilostane can inhibit cortical hormone in the process of synthesis of 3 beta dehydrogenase, make the cortisol, aldosterone synthesis decreased, clinically used in the treatment of Cushing syndrome (hypercortisolism) and primary aldosteronism. This product also had significantly effect to decreased serum testosterone level.

    Trilostane is used in the treatment of Cushing's syndrome. It is normally used in short-term treatment until permanent therapy is possible.

    Trilostane blocks an enzyme involved in the production of several steroids including cortisol. Inhibiting this enzyme inhibits the production of cortisol. In Cushing's syndrome, the adrenal gland overproduces steroids. Although steroids are important for various functions of the body, too much can cause problems. Trilostane reduces the amount of steroids produced by the adrenal gland.

     

    Trilostane produces suppression of the adrenal cortex by inhibiting enzymatic conversion of steroids by 3-beta-hydroxysteroid dehydrogenase/delta 5, 4 ketosteroid isomerase, thus blocking synthesis of adrenal steroids.

     

     

    4 .  COA : 

     

    Test Items Specification Results
    Identification Positive Confirm
    Melting point 257°C to 270°C 261°C -266°C
    Appearance White to pale white solid White solid
    Heavy metals No more than 20ppm 10ppm
    Loss on drying Not more than 0.5% 0.18%
    Residue on Ignition Not more than 0.1% 0.02%

    Solubility

     

     

     

    soluble in dimethyl sulfoxide Conforms
    soluble in pyridine Conforms
    slightly soluble in ethanol Conforms
    slightly soluble in water Conforms
    Assay (microbial) Not less than 99.0% 99.5%
    Specific Rotation +137-139° 137.0°
    Related impurities not more than 1.0% 0.35%
    HPLC purity not less than 99.0% 99.6%
    Solvent Residues Ethanol<5000ppm 1000ppm
    Conclusion Conforms with In-house standard.

     

     

    BP / USP Grade Vetoryl Trilostane Steroids Treatment Cushing Syndrome CAS 13647-35-3

    Contact Details
    Guangzhou Kafen Biotech Co.,Ltd

    Contact Person: Albert Gordon

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