107868-30-4 Chemical Raw Powder Aromasin Exemestane For Aging And Cancer
1 . Quick Details:
Product Name: Exemestane
Alias: Aromasin ; Exemestan
CAS: 107868-30-4
MF: C20H24O2
MW: 296.4
Purity: 99%
Appearance: white solid powder.
Function:Hormones and Regulation of Endocrine Function of Drug, Nutritional Therapeutics, Specialist Drugs
2 . Product Description:
Exemestane (trade name Aromasin) is a drug used to treat breast cancer. It is a member of the class of drugs known asaromatase inhibitors. Some breast cancers require estrogen to grow. Those cancers have estrogen receptors (ERs), and are called ER-positive.They may also be called estrogen-responsive, hormonally-responsive,or hormone-receptorpositive.Aromatase is an enzyme that synthesizes estrogen. Aromatase inhibitors block the synthesis of estrogen. This lowers the estrogen level, and slows the growth of cancers.
Exemestane is an oral steroidal aromatase inhibitor that is used in ER-positive breast cancer in addition to surgery and/or radiation in post-menopausal women.Aromasin is used to fight breast cancer and raise testosterone in the body.Exemestane blocks the process of aromatisation. So it lowers the amount of oestrogen in the body. In early breast cancer, taking exemestane can help to stop breast cancer coming back. In advanced breast cancer the cancer cells may grow more slowly or stop growing completely.
Exemestane is an aromatase inhibitor. This means it blocks the enzyme aromatase (found in the body's muscle, skin, breast and fat), which is used to convert androgens (hormones produced by the adrenal glands) into estrogen. In the absence of estrogen, tumors dependent on this hormone for growth will shrink.
3 . Product Application:
Many breast cancers are stimulated to grow by the female sex hormones oestrogen and progesterone. These breast cancers are called hormone sensitive or hormone receptor positive and can be treated with drugs that block the effects of these hormones.In women who have had their menopause, oestrogen is mainly produced by changing androgens (sex hormones produced by the adrenal glands) into oestrogens. This process is called aromatisation and happens mainly in the fatty tissues, muscle and the skin. It needs a particular enzyme called aromatase.
Exemestane blocks the process of aromatisation. So it lowers the amount of oestrogen in the body. In early breast cancer, taking exemestane can help to stop breast cancer coming back. In advanced breast cancer the cancer cells may grow more slowly or stop growing completely.Hormones are chemical substances that are produced by glands in the body, which enter the bloodstream and cause effects in other tissues.
For example, the hormone testosterone made in the testicles and is responsible for male characteristics such as deepening voice and increased body hair. The use of hormone therapy to treat cancer is based on the observation that receptors for specific hormones that are needed for cell growth are on the surface of some tumor cells. Hormone therapies work by stopping the production of a certain hormone, blocking hormone receptors, or substituting chemically similar agents for the active hormone, which cannot be used by the tumor cell. The different types of hormone therapies are categorized by their function and/or the type of hormone that is affected.
4 . COA:
TEST ITEMS |
SPECIFICATION |
RESULTS |
| Description |
: White Crystalline Powder |
White Powder |
| Identification |
: Positive |
Positive |
| Assay(by HPLC) |
: 98.0~102.0% |
98.64% |
| Absorbance(E1cm) |
: 465~495 |
482.5 |
| Melting Point |
: 191~195°C |
193.5~195.0°C |
| Loss On Drying |
: 0.5%max |
0.19% |
| Specific Rotation |
: +288°~ +298° |
+290.2° |
| Residue On Ignition |
: 0.1%max |
0.03% |
| Related Substances |
: Total:1.5%max |
<1.3% |
| |
Single:0.5%max |
<0.4% |
| Residue Solvents |
: 0.2%max |
0.10% |
| Heavy Metals |
: 20PPm max |
<10PPm |
| Conclusion |
The specification conform with enterprise standard. |
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3: We will sent the package out in 24hours after we received the payment ,then will sent the tracking number with packaging detail to you via mai.
4: We will help track the package until you receive it successful,if accident happen ,we will see the reason to decide re-sent for free or half-price re-sent.
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1. Rich experience: we specialize in this field for many years, our steroids have been exported almost over the world. Such as USA, Canada, UK, Brazil, Germany, Russia, Australia, Greece, Poland, Bulgaria, Rumania, Netherlands, Sweden, Ukraine, Latvia, Lithuania, Ireland, Austria, Iran, Turkey, Mexico, Thailand, India, Malaysia, Singapore, other Middle East countries, European countries, American countries and more Areas.
2. Great quality: High purity and Favorable price. Good quality is the first base of our success. All of our products enjoys high purity. Thus, it can make sure your demand. Welcome order the samples, MOQ just 10 grams.
3. Safe and fast delivery: Lots of different discreet safe packing methods, experience in choosing express, 4~7 days to arrive, successful rate 99%.
4. Experiential order and cooperation: Besides raw powders, we offer hormone solution and Recipes. We can teach you or discuss how to make hormone solution on the site. Any discussion and question is welcome!
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