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White Solid Local Anesthesic Powder Tetracaine Hydrochloride CAS 136-47-0 Pain Killer

White Solid Local Anesthesic Powder Tetracaine Hydrochloride CAS 136-47-0 Pain Killer

  • White Solid Local Anesthesic Powder Tetracaine Hydrochloride CAS 136-47-0 Pain Killer
  • White Solid Local Anesthesic Powder Tetracaine Hydrochloride CAS 136-47-0 Pain Killer
White Solid Local Anesthesic Powder Tetracaine Hydrochloride CAS 136-47-0 Pain Killer
Product Details:
Place of Origin: China
Brand Name: Doublewin
Certification: ISO 9000, SGS
Model Number: 136-47-0
Payment & Shipping Terms:
Minimum Order Quantity: 10kg
Price: Consult me ! Daisy-doublewin@foxmail.com
Packaging Details: Safe packaging
Delivery Time: In 2days time
Payment Terms: T/T, Western Union, MoneyGram,Bitcoin
Supply Ability: 2000kg every month
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Detailed Product Description
Product Name: Tetracaine CAS: 136-47-0
Purity: >99% MF: C15H25ClN2O2
MW: 300.82 Appearance: White Powder
Whatsapp: +8617507260306
High Light:

CAS 136-47-0 Local Anesthesic Powder

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Tetracaine hydrochloride Local Anesthesic Powder

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136-47-0 Tetracaine hydrochloride

White Solid Local Anesthesic Powder Tetracaine hydrochloride CAS 136-47-0 for Pain Killer

 

Product Name: Tetracaine hydrochloride

Product details:

 

Product Name Tetracaine Hydrochloride
Synonym Tetracaine HCL
CAS NO 136-47-0
EINECS 205-248-5
Molecular Formula C15H25ClN2O2
Molecular Weight 300.82
Melting Point 149° C
Assay 99%
Grade Medicine Grade
Storage Closed, confined and shading preservation
Usage Local anesthetic; Mainly used in mucosa anesthetic.
The function is stronger than Procaine and Lidocaine.

 

 

Description:

 

Tetracaine Hydrochloride is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.

 

Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia. In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.

 

 

Application:

 

1) Tetracaine Hcl For block anesthesia and epidural anesthesia.
2) Tetracaine Hcl used for ventricular arrhythmias caused by myocardial infarction, digitalism, glucantime poisoning, surgery and so on. Such as ventricular tachycardia, frequent ventricular premature beat, ventricular fibrillation.
3) Tetracaine Hcl As painkillers of injection in the medicament.
4) Tetracaine Hcl used in suppository and ointment preparation,
5) Tetracaine Hcl has been used in spinal anesthesia.In biomedical research, tetracaine is used to alter the Function of calcium release channels (ryanodine receptors) that control the release of calcium from
Intracellular stores.
6) Tetracaine is an allosteric blocker of channel function.At low concentrations, Tetracaine causes an initial inhibition of spontaneous calcium release events, while at high Concentrations, tetracaine blocks release completely.
Tetracaine hydrochloride has been used for studying the pharmacological effects of spinal anesthesia. A crystalline compound related to procaine and used as a local anesthetic.

 

 

 

 

COA:

 

Test Items Specification Test Results
Appearance Fine, white, crystalline, odorless powder confirm
Identification ABC in Pass confirm
Solubility Very soluble in water, soluble in Alcohol; insoluble in Ether and Benzene confirm
USP Reference standards USP Tetracaine Hydrochloride RS. USP Endotoxin RS. confirm
Melting point 145~150 degree 146.0~147.5
degree
Chromatographic purity In Pass confirm
Related substance Not more than the reference solution 0.05% confirm
Heavy metals ≤10ppm confirm
PH 4.5-6.5 5.8
Residue on ignition ≤0.10% 0.05%
Loss on Drying ≤ 0.5% 0.19%
Assay 98.0 -101.0% 100.1%
Conclusion Confirms USP 32

 

 

Function:

 

Used for mucosal epidermal anesthesia, nerve tissue anesthesia, epidural anesthesia and Subarachnoid space anesthesia. In the manufacture of pharmaceutical preparation for external use, to relieve the pain of drugs or medication lesions pain.

 

Tetracaine hydrochloride is indicated for the production of spinal anesthesia for procedures requiring two to three hours. Parenteral administration of Tetracaine hydrochloride stabilizes the neuronal membrane and prevents initiation and transmission of nerve impulses thereby effecting local anesthesia. The onset of action is rapid, and the duration is prolonged (up to two or three hours or longer of surgical anesthesia).Tetracaine hydrochloride is detoxified by plasma esterases to aminobenzoic acid and diethylaminoethanol.

 

 

White Solid Local Anesthesic Powder Tetracaine Hydrochloride CAS 136-47-0 Pain Killer 0

 
 

 

 

If you have any question,you can feel free to contact me:
Email:Daisy-doublewin@foxmail.com
Whatsapp:+8617507260306

 

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