1-Dehydroepiandrosterone (1-DHEA) is a hormone alternative to standard DHEA supplements
that is more geared for men who wish to look and feel their best. According to scientific
information 1-ene hormones like 1-DHEA may in fact be preferred to standard DHEA (5-DHEA)
for men who wish to use the anti-aging benefits. Standard 5-DHEA found on many store shelves
can have estrogenic side effects that men do not need nor want.
1-Androsterone, or 1-DHEA, may appear under the nomenclature 1-androsten-3b-ol-17-one. 1-
Androsterone is currently available over the counter, and is contained in Iron Mag Labs 1-Andro-
Rx, Advanced Muscle Science 1-Androsterone RD, and Primordial Performance 1-T. 1-
Androsterone is a true prohormone, converting to 1-testosterone (dihydroboldenone). Orally, 1-
Androsterone has about a 10% conversion rate to 1-testosterone. Using this prohormone as a
sublingual (absorbed through the tissues under the tongue) or as a transdermal (absorbed
through the skin) may improve boiavailability, yielding more total 1-testosterone delivered to the
body. 1-Androsterone is great for gains in both strength and size. It does not convert to estrogen
so it is great for cutting cycles or for stacking with compounds that do have estrogenic activity
during a bulking phase. Because 1-Androsterone is non-methylated, it can be stacked with
methylated steroids or prohormones without putting additional stress on the liver.
1- Androsteronetm (1-DHEA) is a non-methylated (non 17aa) pro-steroid that must convert to 1-
androstenediol (1-AD), 1-androstenedione (original 1-AD) and/or 1-testosterone to be active.
The double bond in the 1st position seems to slightly enhance its ability to resist excretion by the
1-Androsterone occurs naturally in the body, and is a naturally occurring metabolite of DHEA. (2)
The 17b-HSD enzyme converts 1-Androsterone to 1-Androstenediol, and the 3b-HSD converts it
to 1-Androstenedione. Both of these 1-AD metabolites can then be converted to 1-Testosterone.
Although the 1-AD metabolites are known to have some anabolic and androgenic effects on their
own, 1-Testosterone is probably where most of the effects come from with this steroid.
There is no conversion to estrogen so users will not experience bloat with this compound, nor will
it have a dramatic effect on blood pressure. However one unique side effect that users have
reported with this compound is a feeling of lethargy. (It appears that stacking 1-Androsterone with
a nuero-active hormone such as DHEA can help reverse this effect).
1-Androsterone (and primarily its metabolites) have relatively potent androgenic effects, therefore
gyno is almost never an issue. However, because of the androgenic potency, this compound
could pose a mild hair loss risk for those prone to MPB. Because this steroid is non-17aa there
should be less concern about it negatively affecting the HDL/LDL ratio.
Results from this compound generally take a couple weeks to be realized. Moderate gains of
lean muscle mass and strength can be expected, but users should not expect rapid increases in
size or weight with this compound since extra-cellular and intra-cellular water retention are very
minimal. This makes the gains from this steroid fairly easy to maintain post cycle.
1-Androsterone will stack well with almost any compound. For more dramatic gains in size and
strength it is recommended to stack this compound with an aromatizing steroid or possibly one of
the progestational compounds listed elsewhere.
The dosing one chooses to work with varies greatly on whether they are stacking this compound
with other anabolics or running it solo. Generally with 1-DHEA 300-600mg a day is the most
popular dosage, however experienced users with past pro-hormone or designer steroid
experience can experiment with dosages in upwards of 700-1000mg. The added benefit may be
negligible at this dosage and the likely-hood of side effects sharply increases..
Since this compound is not as hard on your body cycles can be extended up to 8 weeks in length
with 6 weeks being the most common. Most users will begin to notice the effects by the third
week in the form of muscle hardness/increased strength. Novice users should always stay within
the general dosing amounts and not exceed 6 weeks in cycle length, although more experienced
users can safely run 1-DHEA for 8 weeks.
You should split up your dosages into 2-3 different times throughout the day, ideally separated by
5-6 hours (or 8 hours if two daily dosages). For the ideal results, take your largest dosage 45
minutes to one hour before your workout session.