How does Oxandrolone (Anavar) work?
Anavar increases muscle mass in three ways
1) Inducing protein synthesis in the body
2) Up regulating the androgen receptor in skeletal muscle.
3) Increasing IGF-1 (insulin-like growth factor)
Anavar given to healthy men, has been shown to increase protein synthesis by as much as 44% and improve effects of resistance training.
What are the indications and usage for Anavar (Oxandrolone)?
Anabolic Androgenic Steroids are indicated in patients chronic wasting conditions (the loss of muscle mass) to prevent frailty. Such conditions include sarcopenia, AIDS related muscle wasting, severe burn injury, trauma following surgery and other catabolic disorders. Anavar is approved by the FDA for the treatment of patients with prolonged use of corticosteroids to prevent protein catabolism and has been used to promote weight gain after extensive surgery, during chronic infectious states, or after severe trauma.
How is Oxandrolone (Anavar) absorbed?
Anavar is an oral medication that is absorbed across the gastrointestinal tract. Peak serum concentrations of Anavar occur within 1 hour after ingestion. In the body, Anavar is 95% bound to protein, which may contribute to the steroid’s stability and resistance to breakdown by the liver.
How is Oxandrolone (Anavar) metabolized (broken down)?
Unlike other anabolic steroids, Anavar is rather resistant to liver biotransformation. Approximately 28% of Anavar is excreted in the urine unchanged.
What is the difference between Testosterone and Oxandrolone (Anavar)?
Anavar has a much higher potential to promote anabolic effects on the human body such as an increase muscle size, strength, nitrogen retention, reduce fat deposition and induce protein synthesis compared to testosterone. While testosterone will also promote androgenic affects, Anavar was designed to lessen the unwanted androgenic effects and promote more anabolic properties.
Anavar has much higher anabolic activity compared to testosterone. Anavar has an anabolic: androgenic ratio of 10:1 and a higher steroid protein activity level (SPAI) of 2.8. Testosterone on the other hand has an anabolic: androgenic ration of 1:1 and an SPAI of 1.
How does using Oxandrolone (Anavar) effect Testosterone production?
Anavar usage will decrease the natural pituitary axis necessary to maintain testosterone production. Men who use Anavar will experience a decrease in LH, FSH, SHBG and total and free testosterone. More commonly in men with chronic muscle wasting conditions or HIV wasting, Anavar is combined with testosterone.
Anavar usage has been shown to reduce sex hormone binding globulin (SHBG). Reduction in SHBG reduction increases the amount of free testosterone (active) in the body.
Specifications:
| TEST ITEMS |
SPECIFICATION |
RESULTS |
| Description |
: White or Almost White Crystalline Powder |
white crystalloid powder |
| Identification |
: Positive |
Positive |
| Assay |
: 97.0~100.5% |
98.33% |
| Specific Rotation |
: -18° ~ -24° |
-22.0° |
| Loss On Drying |
: 1.0%max |
0.13% |
| Organic Volatile Impurities |
: meets the requirements |
Conforms |
| Ordinary Impurities |
: 2.0%max |
<2.0% |
| Residual Solvents |
: meets the requirements |
Conforms |
| Residue On Ignition |
: 0.2%max |
0.05% |
| Conclusion |
The specification conform with USP30 standard
|
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