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Clomiphene Citrate CAS 50-41-9 Anti- Infertility Raw Steroid Powders

Clomiphene Citrate CAS 50-41-9 Anti- Infertility Raw Steroid Powders

  • Clomiphene Citrate CAS 50-41-9 Anti- Infertility Raw Steroid Powders
  • Clomiphene Citrate CAS 50-41-9 Anti- Infertility Raw Steroid Powders
  • Clomiphene Citrate CAS 50-41-9 Anti- Infertility Raw Steroid Powders
  • Clomiphene Citrate CAS 50-41-9 Anti- Infertility Raw Steroid Powders
Clomiphene Citrate CAS 50-41-9 Anti- Infertility Raw Steroid Powders
Product Details:
Place of Origin: China
Brand Name: Doublewin
Certification: GMP,ISO,UKAS
Model Number: 50-41-9
Payment & Shipping Terms:
Minimum Order Quantity: 10g
Price: Negotiable
Packaging Details: According to your requirements
Delivery Time: Within 24 hours after receiving your payment
Payment Terms: West Union,Moeny Gram, Bitcoin and Bank Transfer
Supply Ability: 5000KG/Month
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Detailed Product Description
Product Name: Clomiphene Citrate Synonyms: Clomid
CAS No.: 50-41-9 Assay: 99%
Appearance: White Crystalline Powder Usage: Breast Cancer Treatment
Origin: China WhatsApp: +86 17683962426
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Clomiphene Citrate CAS: 50-41-9 Anti- infertility Raw Steroid Powder

 

Clomifene, also known as clomiphene, is a medication used to treat infertility in women who do not ovulate. This includes those who have polycystic ovary syndrome. Use results in a greater chance of twins. It is taken by mouth once a day.

 

Common side effects include pelvic pain and hot flushes.Other side effects can include changes in vision, vomiting, trouble sleeping, ovarian cancer, and seizures.It is not recommended in people with liver disease or who are pregnant.Clomifene is in the selective estrogen receptor modulator (SERM) family of medication.It works by causing the release of gonadotrophin by the hypothalamus.

 

Basic Information:

 

Clomiphene Citrate CAS: 50-41-9
Clomiphene Citrate EINECS:200-035-3
Molecular Formula: C32H36ClNO8
Molecular Weight: 598.08
Clomiphene Citrate Purity: 99% Min Purity
Appearance: White or milky white crystalline powder
Min.Order: 10 Gram Clomiphene Citrate Available
Packing: 1)Aluminum Foil Bag: 100g, 500g, 1Kg 2)Fiber Drum: 25Kg
Delivery Method: HKEMS, DHL, TNT, UPS, FEDEX, EMS, China Air Post etc.
Clearance Rate: 100% Custom Pass, Diguised Package and Safe Delivery
Delivery Time: 5-14 Working Days, Tracking Number Available
Payment Terms: T/T, MoneyGram, and Bitcoin
Origin: Hubei Province, China.

 

COA:

 

Tests Analysis Standard Results
Identification Conform Conform
Absorbance ≤0.30% Conform
Specific Rotation +39°~ +43° +39.5°
Chromatography Purity Conform Conform
17α-Isomer ≤0.50% 0.40%
Organic Volatile Impurities Conform Conform
Loss On Drying ≤0.50% 0.32%
Residue On Ignition ≤0.10% 0.01%
Assay 97~101% 99.02%
Conclusion Be Conform With USP31 Standard

 

Mechanism of Action:

 

Clomiphene was recently reclassified as a selective-estrogen receptor-modulator (SERM) due to its ability to compete with estradiol for estrogen receptors at the level of the hypothalamus. Clomiphene blocks the normal negative feedback of circulating estradiol on the hypothalamus, preventing estrogen from lowering the output of gonadotropin releasing hormone (GnRH). During clomiphene therapy, the frequency and amplitude of GnRH pulses increase and stimulate the pituitary gland to release more FSH and LH. In turn, FSH and LH stimulate the ovaries to develop oocyte follicles. Clomiphene may allow several oocytes to develop to maturity in some patients. Estrogen produced by the maturing follicles causes the cervical mucus to thin and the endometrium to proliferate. As the estradiol from these follicles rises, the positive feedback to the pituitary causes the FSH/LH surge and is followed by mature oocyte release (ovulation). Once ovulation occurs, the corpus luteum forms, and progesterone levels rise as they do in a regular ovulatory cycle, and prepare the endometrium for implantation. Clomiphene must be used before the time of normal selection of the dominant follicle in an ovulatory cycle. The "traditional" timing of clomiphene treatment is from follicular phase cycle day 5 through 9; women typically ovulate 5—10 days after the last dose of the cycle. However, earlier initiation of treatment, longer courses (i.e., up to 10 days), or higher clomiphene doses may be needed dependent on the ovulatory response of the individual woman.

 

Clomiphene is also a weak estrogen-agonist and may interact with estrogen-receptor containing tissues, including the ovary, endometrium, vagina, and cervix. In the cervix, clomiphene can interfere with the ability of cervical mucus glands to produce thin secretions that favor sperm motility and conception. In some women, clomiphene may induce dry, thick cervical secretions. Studies are ongoing to assess the activity of clomiphene on breast tissues. The estrogenic effects of clomiphene are secondary to the primary effects on hypothalamic-pituitary-ovarian function. Clomiphene exhibits no androgenic, anti-androgenic, or progestational effects, nor does it affect pituitary-thyroid or pituitary-adrenal function. After clomiphene therapy discontinuation, there is usually no continued pharmacological effect on subsequent menstrual cycles. However, in some females, spontaneous ovulation has continued.

 

How should I take clomiphene?

 

Use clomiphene exactly as directed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.

 

Your doctor will perform medical tests to make sure you do not have conditions that would prevent you from safely using clomiphene.

 

Clomiphene is usually taken for 5 days, starting on the 5th day of your menstrual period. Follow your doctor's instructions.

 

You will need to have a pelvic examination before each treatment cycle. You must remain under the care of a doctor while you are using this medicine.

 

You will most likely ovulate within 5 to 10 days after you take clomiphene. To improve your chance of becoming pregnant, you should have sexual intercourse while you are ovulating.

 

Your doctor may have you take your temperature each morning and record your daily readings on a chart. This will help you determine when you can expect ovulation to occur.

 

In most cases, clomiphene should not be used for more than 3 treatment cycles.

 

If ovulation occurs but you do not get pregnant after 3 treatment cycles, your doctor may stop treatment and evaluate your infertility further.

 

Store at room temperature away from moisture, heat, and light.

 

 

Clomiphene Citrate CAS 50-41-9 Anti- Infertility Raw Steroid Powders 0

 

 

 

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