Guangzhou Kafen Biotech Co.,Ltd
|Place of Origin:||China|
|Minimum Order Quantity:||As your required.|
|Packaging Details:||According to your requirements.|
|Delivery Time:||Within 24 hours after receiving your payment.|
|Payment Terms:||Western Union,Money Gram,Bank Transfer,Bitcoin|
|Assay:||99%||Appearance:||White Crystal Powder|
Chloramphenicol / Chlornitromycin
Package:25kg/ drum or as required
Usage:can be used as pharmaceutical material
Storage: Shading, confined preservation
Appearance: white crystal powder.
Usage: Genus of broad-spectrum antibacterial antibiotics,it is the treatment of typhoid, paratyphoid medicine, one of the effective drug for the treatment of anaerobic infections, secondly for the treatment of various susceptible disease caused by microbial infections .
Chloramphenicol is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system. Although unpublished, recent research suggests chloramphenicol could also be applied to frogs to prevent their widespread destruction from fungal infections. It has recently been discovered to be a life-saving cure for chytridiomycosis in amphibians.
The most serious adverse effect associated with chloramphenicol treatment is bone marrow toxicity, which may occur in two distinct forms: bone marrow suppression, which is a direct toxic effect of the drug and is usually reversible, and aplastic anemia, which is idiosyncratic (rare, unpredictable, and unrelated to dose) and generally fatal.
Because of its excellent blood-brain barrier penetration (far superior to any of the cephalosporins), chloramphenicol remains the first-choice treatment for staphylococcal brain abscesses. It is also useful in the treatment of brain abscesses due to mixed organisms or when the causative organism is not known.
Use of intravenous chloramphenicol has also been associated with gray baby syndrome, a phenomenon resulting from newborn infants' inability to metabolize chloramphenicol in the body. Other less serious reactions include fever, rashes, headache, and confusion. Prescription use is usually associated with monitoring of a patient's complete blood count. The drug should be discontinued upon appearance of reticulocytopenia, leukopenia, thrombocytopenia, anemia, or any other abnormal blood study findings attributable to chloramphenicol.
|APPEARANCE||white or yellow-white
|yellow-white crystalline powder|
|CRYSTALLINITY||meets the requirements||PASS|
Reaction of chlorides.
|MELTING POINT||149.0~153.0 °C||150~151°C|
|SPECIFIC OPTICAL ROTATION||+18.5 ~ +20.5||+19.6|
|Acidity or alkalinity||Not more than 0.1ml||Confirm|
|LOSS ON DRYING||≤0.5%||0.0%|
|RELATED SUBSTANCES (TCL)||≤0.5%||PASS|
|ASSAY (ON THE DRIED BASIS)||98.0%-~102.0%||99.6%|
Chloramphenicol and chloramine benzyl alcohol, which is produced by chlorine chain thermosphacta has inhibiting effect on bacteria growth of broad spectrum antibiotics, natural chloramphenicol is lefthanded body (also called left toxin).And finished product is white or light yellow acicular or crystal plate, odourless, taste very bitter, slightly soluble in water, ether and chloroform, soluble in methanol, ethanol, acetone or ethyl acetate, insoluble in benzene and petroleum ether.
Antibacterial, antirickettsial, inhibits protein synthesis Usage Chloramphenicol is unusual nitroaromatic metabolite produced by Streptomyces venezuelae, first published in 1947. Chloramphenicol is a broad spectrum antibiotic with good activity against Gram negative and anaerobic bacteria. Although restricted to ocular use, antibiotic resistance to other classes has refocused attention on this class. Chloramphenicol acts by binding to the 23S sub-unit of the 50S ribosome, inhibiting protein synthesis. Chloramphenicol has been extensively studied with over 35,000 literature citations.
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