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Estriol Female Anti Estrogen Steroids Raw Pharmaceutical Active Ingredients CAS 50-27-1

Estriol Female Anti Estrogen Steroids Raw Pharmaceutical Active Ingredients CAS 50-27-1

  • Estriol Female Anti Estrogen Steroids Raw Pharmaceutical Active Ingredients CAS 50-27-1
  • Estriol Female Anti Estrogen Steroids Raw Pharmaceutical Active Ingredients CAS 50-27-1
  • Estriol Female Anti Estrogen Steroids Raw Pharmaceutical Active Ingredients CAS 50-27-1
  • Estriol Female Anti Estrogen Steroids Raw Pharmaceutical Active Ingredients CAS 50-27-1
Estriol Female Anti Estrogen Steroids Raw Pharmaceutical Active Ingredients CAS 50-27-1
Product Details:
Place of Origin: China
Brand Name: Doublewin
Certification: GMP,ISO,UKAS
Model Number: 50-27-1
Payment & Shipping Terms:
Minimum Order Quantity: 10g
Price: Negotiable
Packaging Details: According to your requirements.
Delivery Time: Within 24 hours after receiving your payment.
Payment Terms: Western Union,Money Gram,Bank Transfer,Bitcoin
Supply Ability: 1000KG/Month
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Detailed Product Description
Product Name: Estriol CAS: 50-27-1
Assay: 99% Appearance: White Crystalline Powder
MF: C18H24O3 MW: 288.38
High Light:

estrogen blocker steroids

,

antiandrogen drug

Basic Info.

 

Estriol
Synonyms: 50-27-1, steroid powder, Estriol
CAS No.: 50-27-1
Formula: C18H24O3
Molecular Weight: 288.39
EINECS: 200-022-2
Density: 1.255 g/cm3
Melting Point: 280-282 ° C(lit. )
Boiling Point: 469 ° C at 760 mmHg
Flash Point: 220.8 ° C
Purity: 99%
Appearance: White crystalline powder


Description:

 

Estradiol, or more precisely, 17β-estradiol, is a human sex hormone and steroid, and the primary female sex hormone. It is named for and is important in the regulation of the estrous and menstrual female reproductive cycles. Estradiol is essential for the development and maintenance of female reproductive tissues but it also has important effects in many other tissues including bone. While estrogen levels in men are lower compared to women, estrogens have essential functions in men as well. Estradiol is found in most vertebrates as well as many crustaceans, insects, fish, and other animal species.

 

Estradiol or oestradiol (American or British English usages), derives from estra-, Gk. οστρο? (oistros, literally meaning "verve or inspiration") and -diol, a chemical name and suffix indicating that this form of steroid and sex hormone is a type of alcohol bearing two hydroxyl groups.

 

Estradiol is produced especially within the follicles of female ovaries, but also in other endocrine (i.e., hormone-producing) and non-endocrine tissues (e.g., including fat, liver, adrenal, breast, and neural tissues). Estradiol is biosynthesized from progesterone (arrived at in two steps from cholesterol, via intermediate pregnenolone). One principle pathway then converts progesterone to its 17-hydroxy-derivative, and then to androstenedione via sequential cytochrome P450-catalyzed oxidations.Action of aromatase on this dione generates estrone, and action of a dehydrogenase on this gives the title compound, 17β-estradiol.

 

Application:


Hormonal contraception:

A chemical derivative of estradiol, ethinyl estradiol with maximum dosage 200 µg, is a major component of hormonal contraceptive devices. Combined forms of hormonal contraception contain ethinyl estradiol and a progestin, which both contribute to the inhibition of GnRH, LH, and FSH, which accounts for the ability of these birth control methods to prevent ovulation and thus prevent pregnancy. Other types of hormonal birth control contain only progestins and no ethinyl estradiol.


Hormone replacement therapy:

If severe side effects of low levels of estradiol in a woman's blood are experienced (commonly at the beginning of menopause or after oophorectomy), hormone replacement therapy may be prescribed. Such therapy is usually combined with a progestin to reduce the risk of endometrial cancer.

Estrogen therapy may be used in treatment of infertility in women when there is a need to develop sperm-friendly cervical mucus or an appropriate uterine lining. This is often prescribed in combination with clomifene.

 

Estrogen therapy can also be used to treat advanced prostate cancer, as well as to relieve symptoms of breast cancer.


Not all products are available worldwide. Estradiol is also part of conjugated estrogen preparations, such as Premarin, though it is not the major ingredient. (Premarin consists of a large number of estrogen derivatives. As the name indicates, it comes from pregnant mares' urine.

 

Hormone replacement therapy in transgender women:

Main article: Hormone replacement therapy (male-to-female)
Estrogen therapy is also used as part of the hormone replacement therapy for trans women. Either oral or transdermal estradiol is used in higher concentrations during initial treatment and transition; estradiol is continued in lower doses to maintain female-level hormones following gender reassignment surgery.

 

Blocking estrogens:

Inducing a state of hypoestrogenism may be beneficial in certain situations where estrogens are contributing to unwanted effects, e.g., certain forms of breast cancer, gynecomastia, premature closure of epiphyses, and inhibiting feminization in female-to-male transsexual hormone treatment. Estrogen levels can be reduced by inhibiting production using gonadotropin-releasing factor agonists (GnRH agonists) or blocking the aromatase enzyme using an aromatase inhibitor, or with an estrogen receptor antagonist,.

 

COA:

 

TEST ITEMS SPECIFICATION RESULTS
Description : White or Almost White Crystalline Powder white powder
Identification : A.B. Positive
Assay : 97.0~102.0% 99.3%
Specific Rotation : +101°~+105° +102.6°
Loss On Drying : 1.0%max 0.27%
Melting Point : 153~157°C 153.0~155.0°C
Organic Volatile Impurities : meets the requirement. Conforms
Related Substances : meets the requirement. Conforms
Residual Solvents : meets the requirement. Conforms
Particle Size : 100% ≤ 20 microns Conforms
Conclusion The specification conform with USP30 standard

 

 

Estriol Female Anti Estrogen Steroids Raw Pharmaceutical Active Ingredients CAS 50-27-1 0

 

 

Email:doublewin-eunice@nandrolonesteroid.com

WhatsApp:+86 17683962426

Skype:eunice1998

 

 

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Order step:

1: After our quation ,you will choose to accept or not.

2: If you decide to have a try, choose a payment method to pay for the order.

3: We will sent the package out in 24hours after we received the payment ,then will sent the tracking number with packaging detail to you via mai.

4: We will help track the package until you receive it successful,if accident happen ,we will see the reason to decide re-sent for free or half-price re-sent.


Our Competitive Advantages:
1. Rich experience: we specialize in this field for many years, our steroids have been exported almost over the world. Such as USA, Canada, UK, Brazil, Germany, Russia, Australia, Greece, Poland, Bulgaria, Rumania, Netherlands, Sweden, Ukraine, Latvia, Lithuania, Ireland, Austria, Iran, Turkey, Mexico, Thailand, India, Malaysia, Singapore, other Middle East countries, European countries, American countries and more Areas.
2. Great quality: High purity and Favorable price. Good quality is the first base of our success. All of our products enjoys high purity. Thus, it can make sure your demand. Welcome order the samples, MOQ just 10 grams.
3. Safe and fast delivery: Lots of different discreet safe packing methods, experience in choosing express, 4~7 days to arrive, successful rate 99%.
4. Experiential order and cooperation: Besides raw powders, we offer hormone solution and Recipes. We can teach you or discuss how to make hormone solution on the site. Any discussion and question is welcome!

Packaging & Service:
1. Mass stock, to make sure delivery promptly every day when the payment is done.
2. Having been engaged in this field for years, we have sophisticated and professional logistics department, which can guarantee safe and speedy delivery.
3. Well-trained and disciplined packing team which is professional enough to provide you a safe package. It also avoid a lot of emergency happen during the delivery so that high customs pass is guaranteed. Unique ways to ship 10grams to 20 kilograms powders(or 100ml to 30 Liter liquids) at one time to your destination.
4. Packing pictures and tacking number are provided within 24 hours as soon as receiving the payment. Updated tracking code will be provided every other day just for you can hold a palm of your package.
5. Perfect after-sale service: Any questions or problems happened after receiving the product.
Please feel free to contact us. 24/7 online to solve your various problems!

 

 

Contact Details
Shanghai Doublewin Bio-Tech Co., Ltd.

Contact Person: Eunice

Tel: +86 17683962426

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