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Pharmaceutical Grade Sarms Steroids Reducing Fat Mass Chemicals SR 9011 CAS 1379686-29-9

Pharmaceutical Grade Sarms Steroids Reducing Fat Mass Chemicals SR 9011 CAS 1379686-29-9

    • Pharmaceutical Grade Sarms Steroids Reducing Fat Mass Chemicals SR 9011 CAS 1379686-29-9
    • Pharmaceutical Grade Sarms Steroids Reducing Fat Mass Chemicals SR 9011 CAS 1379686-29-9
  • Pharmaceutical Grade Sarms Steroids Reducing Fat Mass Chemicals SR 9011 CAS 1379686-29-9

    Product Details:

    Place of Origin: China
    Brand Name: Kafen
    Certification: GMP,ISO,UKAS
    Model Number: 1379686-29-9

    Payment & Shipping Terms:

    Minimum Order Quantity: As your required.
    Price: Negotiable
    Packaging Details: According to your requirements.
    Delivery Time: Within 24 hours after receiving your payment.
    Payment Terms: Western Union,Money Gram,Bank Transfer,Bitcoin
    Supply Ability: 1000KG/Month
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    Detailed Product Description
    Product Name: SR 9011 CAS: 1379686-29-9
    Assay: 99% Appearance: White Powder
    MF: C23H31ClN4O3S MW: 479.03524

    Basic Info:

    Cas No 1379686-29-9
    Synonyms 3-(((4-chlorobenzyl)((5-nitrothiophen-2-yl)methyl)amino)methyl)-N-pentylpyrrolidine-1-carboxamide
    Formula C23H31ClN4O3S

    Molucelar weight 479.03524


    Product Description:

    SR9011 is a trifunctional methacrylate monomer that provides exceptional adhesion to metal substrates.
    SR9011 is recommended for use in peroxide cured coatings, sealants, and PVC-based plastisols. Usage levels of 5% to 10% by weight are recommended.
    SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV ERB α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure. Treatment of diet induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases.


    Application:

    In vitro: SR9011 was used at 5-10 μM concentration in vitro and in cellular assays.

    In vivo: IP administration of SR9011 was used at 100 mg/kg once or twice per day for 12-30 days in different mouse models.


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    Company Introduction:

    (1) High Quality: Kafen Biotech is a steroids manufacturer with its own lab and factory.
    The purity of our product is tested by our quality department before it is shipped to our clients. Mostly steroids are 99% purity and approved by SGS,CTI and ITS.


    (2) Favorable Price: Our price meets international market performance and we give the best doiscounted price for our new customers and promotioned price for our regular customers.

    (3) Safe Fast Delivery: After receiving your payment,we will have professional package team to arrange your parcel within 12 hours.We can guarantee every goods can be successfully deliveried.

    (4) Available Shipment Way: EMS,HongKong Post,DHL,TNT,UPS,FedEx,Registered Mail,Air Express,Sea Vessel etc.

    (5) After-Sale Service: We can offer you good service after you place an order.At the same time,we can offer you some homebrew recipe to make injection.More service is more available to you.

     

     

     

    Pharmaceutical Grade Sarms Steroids Reducing Fat Mass Chemicals SR 9011 CAS 1379686-29-9

    Contact Details
    Guangzhou Kafen Biotech Co.,Ltd

    Contact Person: Albert Gordon

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