Guangzhou Kafen Biotech Co.,Ltd
|Place of Origin:||China|
|Minimum Order Quantity:||As your required.|
|Packaging Details:||According to your requirements.|
|Delivery Time:||Within 24 hours after receiving your payment.|
|Payment Terms:||Western Union,Money Gram,Bank Transfer,Bitcoin|
|Product Name:||DM 235||CAS:||314728-85-3|
Appearance: White powder
Shelf life: 2 years
Standard: In-house Standard
Usage: For the treatment of Alzheimers Dementia, Cognition Disorder, Neurologic Drugs, Senile Dementia, Acetylcholine Release Enhancers.
This compound is known as an AMPAkine due to exerting most of its actions via the AMPA receptor (one of the three main subsets of glutamate receptors, alongside NDMA and kainate). This enhancement of AMPA function seems to also rely on enhancing signalling via the Glycine binding site of NMDA receptors, although one minimal signalling goes through the NMDA receptor then the benefits on AMPA receptors seem dose-dependent.
Sunifiram (DM-235) is a piperazine derived ampakine drug which acts as a positive allosteric modulator of AMPA receptors, and has nootropic effects in animal studies with significantly higher potency than piracetam. A number of related compounds are known, the best known being unifiram (DM-232).
This enhancement by sunifiram is associated with an increase inphosphorylation of AMPAR through activation of protein kinase II(CaMKII) and an increase in phosphorylation of NMDAR through activation of protein kinase C α (PKCα). More specifically, sunifiram stimulates the glycine-binding site of NMDAR with concomitant PKCαactivation through Src kinase. Enhancement of PKCα activity triggers to potentiate hippocampal LTP through CaMKII activation.Sunifiram improves cognitive deficits via CaM kinase II andprotein kinase C activation.
For the treatment of Alzheimers Dementia, Cognition Disorder, Neurologic Drugs, Senile Dementia, Acetylcholine Release Enhancers.
Sunifiram (DM-235) is a synthetic derivative of Piracetam, although due to breaking the pyrrolidone backbone it is no longer in the Racetam class of drugs (yet by being derived from them, it is still commonly associated with this class).
Sunifiram has mechanisms similar to Nefiracetam in the hippocampus, and similar to that drug sunifiram shows anti-amnesiac properties and is potentially a cognitive enhancer. Its anti-amnesiac activity is several orders of magnitude greater than piracetam on a per weight basis, and preliminary evidence suggest it has a similarly low toxicity profile.
Sunifiram increases energy levels, allowing users to feel more motivated and eliminate
Sunifiram increase Levels of concentration increase, and users feel less distracted by external stimuli
Sunifiram also enhances long-term potentiation, which is the forming of new connections regarding memory storage.
Sunifiram has some anxiolytic benefits. Feeling more relaxed is beneficial when trying to focus.
|Product name||CAS No.||Specification|
(1) High Quality: Kafen Biotech is a steroids manufacturer with its own lab and factory.
The purity of our product is tested by our quality department before it is shipped to our clients. Mostly steroids are 99% purity and approved by SGS,CTI and ITS.
(2) Favorable Price: Our price meets international market performance and we give the best doiscounted price for our new customers and promotioned price for our regular customers.
(3) Safe Fast Delivery: After receiving your payment,we will have professional package team to arrange your parcel within 12 hours.We can guarantee every goods can be successfully deliveried
(4) Available Shipment Way: EMS,HongKong Post,DHL,TNT,UPS,FedEx,Registered Mail,Air Express,Sea Vessel etc
(5) After-Sale Service: We can offer you good service after you place an order.At the same time,we can offer you some homebrew recipe to make injection.More service is more available to you.