Guangzhou Kafen Biotech Co.,Ltd
|Place of Origin:||China|
|Minimum Order Quantity:||10g|
|Packaging Details:||According to your requirements|
|Delivery Time:||Within 24 hours after receiving your payment|
|Payment Terms:||West Union,Moeny Gram, Bitcoin and Bank Transfer|
|Product Name:||PRL-8-53 HCl||MF:||C18H22ClNO2|
Product Name: PRL-8-53 HCl
Chemical name: Methyl 3-(2-(benzyl(methyl)amino)ethyl)benzoate
Synonyms:PRL-8053;PRL-8-53;Methyl 3-(2-(benzyl(Methyl)aMino)ethyl)benzoate hydrochloride;3-(2-Benzyl(methyl)aminoethyl)benzoic acid methyl ester hydrochloride;m-[2-(Benzylmethylamino)ethyl]benzoic acid methyl ester hydrochloride;Benzoic acid, 3-(2-(Methyl(phenylMethyl)aMino)ethyl)-, Methyl ester, hydrochloride
Grade: Pharmaceutical Grade
Appearance: White powder
Field: Nootropic medicine
Usage: Used to improve brain circulation
Dosage: Subjects in human trials have been given up to 100 mg a day and did not appear to develop any negative side effects.
PRL-8-53 (chemical name Methyl 3-(2-(benzyl(methyl)amino)ethyl)benzoate) is a synthetic nootropic compound discovered in 1972 and patented in 1975 by the late Dr. Nikolaus Hansl, a neuropharmacologist at Creighton University in Omaha, Nebraska. Preliminary animal tests indicated that the compound was both safe and significantly nootropic, boosting avoidance learning in rodents with no adverse effects. But the real interest in PRL-8-53 was sparked by a 1978 study on human volunteers, which showed that a single dose of the compound could improve word retention scores by more than 200%.
PRL-8-53's exact mechanisms of action are not well understood, but it is generally believed to regulate the brain's production of and response to several crucial neurotransmitters. In his reports on human and animal studies Hansl indicated that PRL-8-53 potentiates dopamine, partially restricts production of serotonin, and enhances the brain's response to acetylcholine.
Though Hansl's research report on the 1978 human study suggests those actions, it does not clearly delineate the mechanism of action.The fact that older subjects saw the most nootropic benefit from taking the drug supports the concept that dopamine modulation plays a major role in PLR-8-53's effects. Up-regulating the normal age-related lessening of dopamine production that is associated with cognitive decline could have a significant positive impact on both learning and memory.
The only human study on PRL-8-53 was based on the ingestion of a single 5 mg dose. There is no data on the effectiveness or potential toxicity of any other dosage in humans.
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2 years, keep in formal storage condition.
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Shipment Time:Within 12 hours after confirmation of your payment
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