1.Basic Info.
Product Name: Flurbiprofen
Flurbiprofen Synonyms: 1'-biphenyl)-4-aceticacid,2-fluoro-alpha-methyl-(;1'-biphenyl]-4-aceticacid,2-fluoro-alpha-methyl-[;2-(2-Fluoro-4-biphenyl)propionicacid;2-(2-fluoro-4-biphenylyl)propionicacid;2-fluoro-alpha-methyl-4-biphenylaceticaci;2-Fluoro-a-methyl-(1,1'-biphenyl)-4-aceticacid;bts18322;fp70
Flurbiprofen CAS: 5104-49-4
Flurbiprofen MF: C15H13FO2
Flurbiprofen MW: 244.26
Flurbiprofen EINECS: 225-827-6
Flurbiprofen Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;API's;Aromatics;API;ANSAID;Other APIs
2.Product Description
Flurbiprofen is a nonsteroidal anti-inflammatory drug (NSAID). It may cause an increased risk of serious and sometimes fatal heart and blood vessel problems (eg, heart attack, stroke). The risk may be greater if you already have heart problems or if you take flurbiprofen for a long time. Do not use flurbiprofen right before or after bypass heart surgery.
Flurbiprofen may cause an increased risk of serious and sometimes fatal stomach ulcers and bleeding. Elderly patients may be at greater risk. This may occur without warning signs.
3.Product Applications:
Flurbiprofen is a member of the phenyl alkanoic acid derivative family of non-steroidal anti-inflammatory drugs (NSAIDs) used to treat the inflammation and pain of arthritis. It is known as "Ansaid" marketed by and "Froben" by Abbott. Flurbiprofen is also used as an active ingredient in some kinds of throat lozenges (Strepsils Intensive).
A single enantiomer of flurbiprofen, tarenflurbil [(R)-flurbiprofen)], is currently in clinical trials for the treatment of metastatic prostate cancer. 3. Drug Class and Mechanism: Flurbiprofen is a nonsteroidal anti-inflammatory drug (NSAID) effective in treating fever, pain, and inflammation in the body. It is similar to ibuprofen (Motrin or Advil), naproxen (Naprosyn), and others.
As a group, NSAIDs are non-narcotic relievers of mild to moderate pain of many causes, including injury, menstrual cramps, arthritis, and other musculoskeletal conditions. They work by reducing the levels of prostaglandins, chemicals that are responsible for pain, fever, and inflammation. Flurbiprofen blocks the enzyme that makes prostaglandins (cyclooxygenase), resulting in lower concentrations of prostaglandins. As a consequence, inflammation, pain and fever are reduced. The FDA approved flurbiprofen in October 1988.
Treating rheumatoid arthritis or osteoarthritis. It may also be used for other conditions as determined by your doctor.Flurbiprofen is an NSAID. Exactly how it works is not known. It may block certain substances in the body that are linked to inflammation. NSAIDs treat the symptoms of pain and inflammation. They do not treat the disease that causes those symptoms.
How to use flurbiprofen:
Use flurbiprofen as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Flurbiprofen comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get flurbiprofen refilled.
Take flurbiprofen by mouth. It may be taken with food if it upsets your stomach. This may not lower the risk of stomach or bowel problems (eg, bleeding, ulcers). Talk with your doctor if you have persistent stomach upset.Take flurbiprofen with a full glass of water (8 oz/240 mL) as directed by your doctor.
If you miss a dose of flurbiprofen and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose. Go back to your regular dosing schedule. Do not take 2 doses at once.Ask your health care provider any questions you may have about how to use flurbiprofen.
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