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99% Purity Abiraterone Powder CAS154229-19-3 For Prostate Cancer Treatment

99% Purity Abiraterone Powder CAS154229-19-3 For Prostate Cancer Treatment

  • 99% Purity Abiraterone Powder CAS154229-19-3 For Prostate Cancer Treatment
  • 99% Purity Abiraterone Powder CAS154229-19-3 For Prostate Cancer Treatment
  • 99% Purity Abiraterone Powder CAS154229-19-3 For Prostate Cancer Treatment
99% Purity Abiraterone Powder CAS154229-19-3 For Prostate Cancer Treatment
Product Details:
Place of Origin: China
Brand Name: Doulewin
Certification: GMP,ISO,UKAS
Model Number: 154229-19-3
Payment & Shipping Terms:
Minimum Order Quantity: 10g
Price: Negotiable
Packaging Details: According to your requirements
Delivery Time: Within 24 hours after receiving your payment
Payment Terms: West Union,Moeny Gram, Bitcoin and Bank Transfer
Supply Ability: 5000KG/Month
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Detailed Product Description
Product Name: Abiraterone Synonyms: 17-(3-Pyridyl)androsta-5,16-dien-3beta-ol
CAS No.: 154229-19-3 Assay: 99%
Appearance: White Powder Usage: Prostate Cancer,Breast Cancer
High Light:

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1.Basic info.


Product name:Abiraterone
Alias : 17-(3-Pyridyl)androsta-5,16-dien-3beta-ol
CAS register number: 154229-19-3
Molecular Formula: C24H31NO
Molecular Weight: 349.51
Molecular Structure:
Assay: 99%
Appearance: White powder
Grade: Pharmaceutical Grade
Storage: Shading, confined preservation
Usage: It is indicated for use in combination with prednisone as a treatment for metastatic castration-resistant prostate cancer.


2.Product Description:
 

Abiraterone is a new type of hormone therapy. It is also called abiraterone acetate. It is used to treat prostate cancer that has spread to other parts of the body. It may help some men to live longer. It can also help control symptoms. Clinical trials are also using abiraterone for earlier stages of prostate cancer and advanced breast cancer. Abiraterone is associated with a not uncommon rate of serum enzyme elevation during therapy, but has not been clearly linked to cases of clinically apparent liver injury with jaundice.

Abiraterone is a steroidal compound with antiandrogen activity. it is a Cytochrome P450 17A1 Inhibitor. The mechanism of action of abiraterone is as a Cytochrome P450 17A1 Inhibitor, and Cytochrome P450 2D6 Inhibitor, and Cytochrome P450 2C8 Inhibitor that catalyzes the 17alpha-hydroxylation of steroid intermediates involved in testosterone synthesis. Administration of this agent may suppress testosterone production by both the testes and the adrenals to castrate-range levels.


3.Product Applications:

 

Abiraterone is a drug used in combination with in metastatic castration-resistant prostate cancer (formerly hormone-resistant or hormone-refractory prostate cancer) -- i.e., prostate cancer not responding to androgen deprivation or treatment with antiandrogens. It is formulated as the prodrug abiraterone acetate and marketed under the trade name Zytiga. Cadila Pharmaceuticals has recently started marketing Abiraterone acetate under the trade name Abretone.


After an expedited six-month review, abiraterone was approved by the U.S. Food and Drug Administration (FDA) in April 2011. In Phase III trials, it extended median survival to 14.8 months versus 10.9 months placebo, and the trial was stopped because of the successful outcome.


4.Hot product :

 


Items
Specifications Results
Appearance A White or almost white crystalline powder white powder
Solubility Freely soluble in methylene chloride,acetone and in THF,hardly soluble in n-Heptane Conform
Identification A).By IR: Positive
 
Conform
B).By HPLC: Positive Conform
Specific Rotation -370to -450 -420
Residue on ignition 0.2% max 0.07%
Loss on drying 1.0% max 0.22%
Heavy metals 20ppm max Conform
Related Substance
(by HPLC)
Unspecified impurity: 0.1% max 0.08%
Total impurities: 0.5% max 0.33%
Residual solvents Methanol:3000ug/g max 1160
Methylene chloride: 600ug/g max Not detected
THF: 720ug/g max Not detected
Acetic acid:5000ug/g max Not detected
Storage condition Preserve in tight,light-resistant contaners,and store at room temperatura.
Assay (on anhydrous basis) 98.0% to 102.0% 99.7%

 

 

99% Purity Abiraterone Powder CAS154229-19-3 For Prostate Cancer Treatment 0

 

 

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WhatsApp:+86 17683962426

Skype:eunice1998

 

 

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3. Safe and fast delivery: Lots of different discreet safe packing methods, experience in choosing express, 4~7 days to arrive, successful rate 99%.
4. Experiential order and cooperation: Besides raw powders, we offer hormone solution and Recipes. We can teach you or discuss how to make hormone solution on the site. Any discussion and question is welcome!

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