| Product Name: |
Testolactone |
| Synonyms: |
TESTOLACTONE;1Teslac;1,2-Didehydrotestololactone;1,2-dehydrotestololactone;1,2-didehydro-testololacton;17alpha-oxo-d-homo-1,4-androstadiene-3,17-dione;17-secoandrosta-1,4-dien-17-oicacid,13-hydroxy-3-oxo-1delta-lactone;1-dehydrotestololactone;delta(1)-dehydrotestolactone |
| CAS: |
968-93-4 |
| MF: |
C19H24O3 |
| MW: |
300.39 |
| EINECS: |
213-534-6 |
| Product Categories: |
Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids |
| Mol File: |
968-93-4.mol |
 |
Testolactones Used:
Treating certain types of breast cancer in women who have been through menopause or whose ovaries no longer function. It may also be used for other conditions as determined by your doctor.
Testolactones is an antineoplastic that is related to testosterones (male sex hormone) but has not been shown to have the masculine effects of testosterones.
It works by blocking the production of estrogen, which helps prevent the growth of breast cancers that are activated by estrogen. It may also prevent tumor cells from being activated by other hormones.
(1) Testolactonse - classified as an antineoplastic agent:
Testolactones is approved by the United States Food and Drug Administration (FDA), and its cost usually is covered by insurance. It is classified as an antineoplastic agent, which means that it stops or slows the growth of malignant cells.
One advantage of testolactones is that, although it is related to testosterones, it does not cause women to develop male characteristics such as a deep voice or facial hair.
(2) Related to the male hormone testosterones:
Testolactones is related to the male hormone testosterones. The way in which it inhibits the growth of breast cancer cells is not clear.
However, it is known that the hormone estrogen stimulates the growth of some breast cancer cells, and testolactones seems to interfere with estrogen production. The resulting reduction in estrogen levels may slow the growth of breast cancers sensitive to this hormone.
(3) A palliative treatment:
In breast cancer, testolactonses is a palliative treatment. This means that it helps relieve symptoms, but does not cure the cancer. It is effective only in about 15% of the women who take it. In these women, however, it helps reduce the size of half or more tumors. Normally testolactones is used along with other chemotherapy drugs for fighting advanced breast cancer.
(4) Dosage:
Testolactones comes as a 50 mg tablet. The dose will depend on the patient's body weight and her general health, as well as other drugs she may be taking.
However, a standard dose is 250 mg (5 tablets) four times a day for three months. It takes at least several weeks before the drug begins to be effective. Tablets should be stored at room temperature.
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