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202138-50-9 Pharma Antiviral Agents Tenofovir Disoproxil Fumarate For Medicine Ingredients

202138-50-9 Pharma Antiviral Agents Tenofovir Disoproxil Fumarate For Medicine Ingredients

    • 202138-50-9 Pharma Antiviral Agents Tenofovir Disoproxil Fumarate For Medicine Ingredients
    • 202138-50-9 Pharma Antiviral Agents Tenofovir Disoproxil Fumarate For Medicine Ingredients
    • 202138-50-9 Pharma Antiviral Agents Tenofovir Disoproxil Fumarate For Medicine Ingredients
  • 202138-50-9 Pharma Antiviral Agents Tenofovir Disoproxil Fumarate For Medicine Ingredients

    Product Details:

    Place of Origin: China
    Brand Name: kafen
    Certification: USP, GMP ,ISO9001, UKAS,BP
    Model Number: Tenofovir

    Payment & Shipping Terms:

    Minimum Order Quantity: 10g
    Price: Negotiable
    Packaging Details: Disguised and discreet or according to every customer's requirements
    Delivery Time: Within 12 hours after receiving your payment
    Payment Terms: T/T, Western Union, MoneyGram,Bitcoin
    Supply Ability: 800-1000kg/Month
    Contact Now
    Detailed Product Description
    Product Name: Tenofovir CAS: 202138-50-9
    MF: C9H14N5O4P MW: 287.21
    Purity: 99% Appearance: White Powder

    CAS 202138-50-9 Pharma Antiviral Agents Tenofovir for Medicine Ingredients

     

     

    Basic info:

    Tenofovir
    CAS:147127-20-6
    MF: C9H14N5O4P
    MW:287.21
    mp:276-280°C
    storage temp. Store at -20°C
    Water Solubility :13.4 mg/mL (25 ºC)
    Chemical Properties:White Crystalline Solid
    Usage:Acyclic phosphonate nucleotide analogue. Used as an anti-HIV agent
    Usage:Acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.
    Usage:Tenofovir blocks reverse transcriptase and hepatitis B virus infections.
    Biological Activity Selectively inhibits HIV reverse transcriptase (RNA-dependent DNA polymerase). Prevents cytotoxicity in SIV-infected C-8166 cells in vitro (IC 50 = 1.5 μ M). Antiviral agent.

     

     

    Tenofovir Usage And Synthesis:

    1. Antiviral drugs, Tenofovir is an acyclic nucleoside antiviral reverse transcriptase inhibitor. The active substance is Tenofovir disoproxil, while tenofovir is a prodrug that is used because of its better absorption in the gut.


    2. Tenofovir can inhibit viral polymerase through direct competitively combine with natural deoxyribose or by insertion to terminate chain of human DNA. It is the first nucleotide analogs to treat HIV-1 infection that approved by the US Food and Drug Administration (FDA).


    3. Tenofovir is a main medicine in AIDS cocktail therapy, researches has shown that it can effectively improve the monkeys` ability on prevention of immunodeficiency virus (similar to the human AIDS virus).

     

     

    Pharmacokinetics:

    Tenofovir is hardly absorbed through the gastrointestinal tract, for this reason, prodrug of Tenofovir has been developed by esterification, and then to make tenofovir fumarate ester. Tenofovir ester is water-soluble, can be rapidly absorbed and degraded into the active tenofovir, and then was metabolized to the active Tenofovir disoproxil. Tenofovir will reach the peak of plasma Concentration within 1-2 h after administration. When combined with food service, the bioavailability of Tenofovir can be increased by 40%. Intracellular half-life of Tenofovir disoproxil is about 10 h, it needs dosing everyday. Because Tenofovir is not a CYP-450 substrate, this may decrease the possibility of interactions with other drugs caused by CYP450. Elimination of Tenofovir is by glomerular filtration and active tubular secretion. Approximately 70% to 80% is recovered in urine as unchanged drug. Elimination half-life is approximately 17 h.

    Indications: Tenofovir is indicated for the treatment of HIV, HBV infection. This product also can cooperated with other reverse transcriptase inhibitors for HIV-1 infection and hepatitis B treatment.

     

     

    Delivery and Packaging :

    We have professional team for package and shipment. Special way to ship 100 grams to 100kg powders at one time to your country. Fast and discreet shipment could be arranged for customs pass Guaranteed.

     


    Competitive Advantage:

    1. Rich experience.
    Having been specialized in this field for years, we have rich experience and widespread sales network around the word. Our steroid and hormones have been exported to overseas, like Europe, Africa, Asia, America and other countries. We are not got good feedback from our guest, but also established long business relationship with them.

    2. Great quality and high purity.
    Good quality is one secret for our success. All of our products enjoys high purity. Thus, it can make sure our client's need. Welcome order the samples, MOQ just 10 grams.

    3. Safest and fastest delivery.
    We have mass stock, so that we can arrange the delivery within 24hours once receiving the payment. Tracking number would be informed quickly after shipment. We have our own way of packing which could ship 0.01 kilo to 50 kilo products a time.

    4. Good after-sales service.
    24/7 is available. We will tell you the package updated info ASAP. And try our best to solve various problems customers encountered!

    5. Experiential shopping.
    Besides raw steroid powder and liquid, we offer hormone solution and formula. We can teach you how to make hormone solution on the site. Any visit to our lab is welcomed.

     

     

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    202138-50-9 Pharma Antiviral Agents Tenofovir Disoproxil Fumarate For Medicine Ingredients

    Contact Details
    Guangzhou Kafen Biotech Co.,Ltd

    Contact Person: Albert Gordon

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