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99% Purity Anti Estrogen Steroids Chlormadinone Acetate Powder CAS 302-22-7

99% Purity Anti Estrogen Steroids Chlormadinone Acetate Powder CAS 302-22-7

    • 99% Purity Anti Estrogen Steroids Chlormadinone Acetate Powder CAS 302-22-7
    • 99% Purity Anti Estrogen Steroids Chlormadinone Acetate Powder CAS 302-22-7
  • 99% Purity Anti Estrogen Steroids Chlormadinone Acetate Powder CAS 302-22-7

    Product Details:

    Place of Origin: China
    Brand Name: Kafen
    Certification: GMP,ISO,UKAS
    Model Number: 302-22-7

    Payment & Shipping Terms:

    Minimum Order Quantity: 10g
    Price: Negotiable
    Packaging Details: According to your requirements
    Delivery Time: Within 24 hours after receiving your payment
    Payment Terms: West Union,Moeny Gram, Bitcoin and Bank Transfer
    Supply Ability: 5000KG/Month
    Contact Now
    Detailed Product Description
    Product Name: Chlormadinone Acetate MF: C23H29ClO4
    CAS No.: 302-22-7 Assay: 99%
    Appearance: Yellow Crystalline Powder Use: Medecine Intermediate

    1.Basic Info.


    Product Name:Chlormadinone acetate
    CAS NO.: 302-22-7
    EINECS:206-118-0
    Assay: 99%
    Molecular Formula: C23H29ClO4
    Molecular Weight:404.93
    Specification: CP2000, JP14
    Packing:foil bags
    Delivery: in 24 hours after payment.
    The min. order:10 grams.
    Appearance:yellow crystalline powder

     


    2.Product Description:

     

    Chlormadinone acetate (CMA) is a derivative of progesterone (17-acetoxy-6-chloro-4,6-pregnadiene-3,20-dione), first synthesized in 1961 and is used as an orally effective progestogen in hormone replacement therapy (HRT), and in combination with ethinyl estradiol (EE) in contraception since 1999.

    Chlormadinone acetate has a strong progestogenic effect about one-third higher than that of progesterone and may vary depending on the previous effect of an estrogen, i.e., estrogens may promote the formation of progesterone receptors and proliferation of the endometrium. Like progesterone, it is anti-estrogenic and has no partial androgenic effect (at the doses used for contraception and HRT).

    In contrast to progesterone, it has a slight glucocorticoid effect, a pronounced anti-androgenic effect and no anti-mineralocorticoid effect. No pregnancy-maintaining effect of CMA has been demonstrated in humans.

    The anti-androgenic effect of CMA is presumed to be the result of both its binding to androgen receptors competitively inhibiting the effect of endogenous testosterone and dihydrotestosterone and the competitive inhibition of 5-reductase. In this respect, dosing of CMA is crucial; agonistic effects are observed when doses are increased from those optimal for an antagonistic effect.

    Chlormadinone acetate has a strong anti-gonadotropic effect, through negative feedback on gonadotropin secretion, and has been used for more than 20 years alone for contraception in arterial risk patients. The clinical and metabolic tolerability of CMA has been demonstrated in numerous clinical studies with duration of treatment of up to 2.5 years.

    The more recent application of CMA as an oral contraceptive in combination with EE (Neo Eunomin, Belara) has proven highly successful, with studies reporting excellent contraceptive efficacy, high tolerability and adherence due to a good side effect profile and positive effects on preexisting dysmenorrhea, skin and hair conditions.

     

    3.Product Application:

     

    Chlormadinone acetate (CMA) is a derivative of naturally secreted progesterone that shows high affinity and activity at the progesterone receptor. It has an anti-estrogenic effect and, in contrast to natural progesterone, shows moderate anti-androgenic properties.

    CMA acts by blocking androgen receptors in target organs and by reducing the activity of skin 5alpha-reductase. It suppresses gonadotropin secretion and thereby reduces ovarian and adrenal androgen production.

    CMA shows high contraceptive efficacy by inhibiting ovulation due to its ability to suppress or disrupt endogenous gonadotropin secretion and, by this, inhibits follicular growth and maturation. In addition, it suppresses endometrial thickness and increases the viscosity of cervical mucus.

     

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    Shipping & Delivery
    1.Packages are generally dispatched within approximately 2 days after receipt of payment.
    2.After the each shipping we will provide you with:
    1) a link & tracking number to track your package online.
    2) the few pictures with your order & details.
    3.About the Custom clearance,we packed in disguise ways.In our experience,the appropriate and safe delivery,there won't be problems.
    4.We confirm 99% clearance,100% resending.
    5.Is it the best & safest shipping for all our repeat customers!

     

    Packing Details
    Discreet packing ways as your requirement, 100% go through.
    Storage
    Store in cool and dry area and keep away from direct sunlight.oC
    Shelf life
    2 years, keep in formal storage condition.
     
    MOQ
    We accept any Qty you require, grams to kilograms.
    Samples Available, Contact now!
     
    Top reason why you choose us ?
    (1)Fast discreet delivery with great shipping success!
    (2)Pictures with your order & details!
    (3)We will provide you the tracking number!
    (4)Keep track of your goods untill the goods are sent in to your hands.
    (5)We confirm 99% clearance,100% resending.
    (6)High quality,100% pure products!
    (7)Delivery time approx.4-6 business days.
    (8)Best, Safe and Secure services.
    (9)Customer support 24/7.


    Order infos
    Payment Methods:West Union,Moeny Gram, Bitcoin and Bank Transfer.
    Delivery Ways:EMS,HKEMS,TNT,DHL,FedEX,UPS etc.
    Shipment Time:Within 12 hours after confirmation of your payment
    Other Service:Safe shipment,high purity and best price for you.

    99% Purity Anti Estrogen Steroids Chlormadinone Acetate Powder CAS 302-22-7

    Contact Details
    Guangzhou Kafen Biotech Co.,Ltd

    Contact Person: Eunice

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