Guangzhou Kafen Biotech Co.,Ltd
|Place of Origin:||china|
|Certification:||SGS, UKAS, ISO9001|
|Minimum Order Quantity:||No limit|
|Packaging Details:||According to your require ments|
|Delivery Time:||3-5 day|
|Payment Terms:||T/T, Western Union, MoneyGram|
White Powder Prohormones Steroids Trilostane For Breast Cancer Treatment 13647-35-3
Molecular Weight: 329.4333
Molecular Formula: C20H27NO3
Melting point: 264° C
Storage: Shading, confined preservation
Appearance: White crystalline powder
Payment:T/T, Western Union and Money Gram
Delivery:Within 24hours After Your Payment
Express: EMS, DHL, FedEx, etc(door-to-door)
Trilostane is an inhibitor of 3β -hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome and primary hyperaldosteronism. These are both disorders where excess amounts of corticosteroid hormones are produced in the body. Corticosteroids are essential for the body to make use of carbohydrates, fats and proteins and for a normal response to stress. They are also necessary for the regulation of salt and water balance in the body. Trilostane helps prevent the production of corticosteroids, controlling the symptoms associated with these disorders.
Trilostane can inhibit cortical hormone in the process of synthesis of 3 beta dehydrogenase, make the cortisol, aldosterone synthesis decreased, clinically used in the treatment of Cushing syndrome (hypercortisolism) and primary aldosteronism. This product also had significantly effect to decreased serum testosterone level.
Trilostane can also be useful in the treatment of breast cancer that has relapsed in women who have gone through menopause.
Trilostane is used in the treatment of Cushing's syndrome. It is normally used in short-term treatment until permanent therapy is possible.
Trilostane blocks an enzyme involved in the production of several steroids including cortisol. Inhibiting this enzyme inhibits the production of cortisol. In Cushing's syndrome, the adrenal gland overproduces steroids. Although steroids are important for various functions of the body, too much can cause problems. Trilostane reduces the amount of steroids produced by the adrenal gland.
Trilostane produces suppression of the adrenal cortex by inhibiting enzymatic conversion of steroids by 3-beta-hydroxysteroid dehydrogenase/delta 5,4 ketosteroid isomerase, thus blocking synthesis of adrenal steroids.
Trilostane is usually given by the inhaled route for direct effect on bronchial smooth muscle. This is usually achieved through a metered dose inhaler (MDI), nebulizer or other proprietary delivery devices (e.g. Rotahaler or Autohaler). In these forms of delivery, the maximal effect of salbutamol can take place within five to 20 minutes of dosing, though some relief is immediately seen. It can also be given intravenously.
Trilostane is also used in the treatment of bronchial asthma, asthmatic bronchitis, emphysema, patients bronchospasm.
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2) All Purity≥98%
3) We are manufacturer and can provide high quality products with factory price.
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1) Parcel can be sent out within 24 hours after payment. Tracking number available
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3) Customs pass rate ≥99%
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3, We have clients throughout the world.
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.
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