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High Quality 99% Pain Killer USP Grade Pramoxine HCL Raw Powder CAS 637-58-1

High Quality 99% Pain Killer USP Grade Pramoxine HCL Raw Powder CAS 637-58-1

High Quality 99% Pain Killer USP Grade Pramoxine HCL Raw Powder CAS 637-58-1

Product Details:

Place of Origin: China
Brand Name: Kafen
Certification: GMP
Model Number: 637-58-1

Payment & Shipping Terms:

Minimum Order Quantity: 10g
Price: Negotiable
Packaging Details: Discreet and disguised
Delivery Time: Within 24 hours after receiving your payment
Payment Terms: Western Union, MoneyGram,Bitcoin and Bank Transfer
Supply Ability: 5000KG/Month
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Detailed Product Description
CAS: 637-58-1 EINECS: 211-293-1
MF: C17H28ClNO3 MW: 329.86
MP: 181-183° Purity: 99%

Pramoxine Hydrochloride Info:


Product Name:Pramoxine Hydrochloride
Synonyms:4-(3-(p-butoxyphenoxy)propyl)-morpholinhydrochloride;gamma-morpholinopropyl4-n-butoxyphenyletherhydrochloride;p-butoxyphenylgamma-morpholinopropyletherhydrochloride;
Proctofoam;Pramoxine Hcl;Pramoxine Hydrochloride;Praxomine Hydrochloride;Tronothane Hydrochloride
CAS:637-58-1
MF: C17H28ClNO3
MW:329.86
EINECS: 211-293-1
Usage:Muscle relaxant (smooth). slows growth of unwanted facial hair.
Packing:1kg/bag

USP36 Local Anesthetic Drugs Pramoxine Hydrochloride / Pramoxine HCl 637-58-1

 

 

 

Description:

 

Pramocaine (INN and BAN, also known as pramoxine or pramoxine HCI) is a topical anesthetic discovered at Abbott Laboratories in 1953 and used as an antipruritic. Chemically, it is p-n butoxyphenyl gammamorpholinopropyl  ether hydrochloride. During research and development, pramoxine hydrochloride stood out among a series of alkoxy aryl alkamine ethers as an especially good topical local anesthetic agent.

 

Pharmacologic study revealed it to be potent and of low acute and subacute toxicity, well tolerated by most mucous membranes and of a low sensitizing index in man. Like other local anesthetics, paramoxine decreases the permeability of neuronal membranes to sodium ions, blocking both initiation and conduction of nerve impulses. Depolarization and repolarization of excitable neural membranes is thus inhibited, leading to numbness.

 

Topical anesthetics are used to relieve pain and itching caused by conditions such as sunburn or other minor burns, insect bites or stings, poison ivy, poison oak, poison sumac, and minor cuts and scratches. Pramocaine and dibucaine are also common ingredients in over the counter hemorrhoid preparations.

 

The popular itch creams Gold Bond and some forms of Calamine Lotion use pramocaine hydrochloride to numb sensitive skin, as does the pain relief variant of Neosporin and some formulations of Sarna. The hydrochloride salt form of pramocaine is water-soluble.

 

Pramoxine belongs to a class of drugs known as local anesthetics. It works by numbing the skin to block the feelings of pain and itching.Pramoxine is used to temporarily relieve itching and pain caused by minor skin irritation such as minor burns/cuts/scrapes, sunburn, eczema, insect bites, cold sores, or rashes from poison ivy, poison oak, or poison sumac. Some products containing pramoxine are also used to temporarily relieve the itching and discomfort from hemorrhoids and certain other problems of the genital/anal area (such as anal fissures, itching around the vagina/rectum).

 

Application:

 

(1) Surgical anesthesia:Epidural anesthesia (including epidural anesthesia during cesarean section);Local infiltration anesthesia.


(2) Acute pain control:For postoperative or labor analgesia continuous epidural infusion can be used can also be intermittent medication;Local infiltration anesthesia.

(3)Pramoxine Hydrochloride are used to relieve pain and itching caused by conditions such as sunburn or
other minor burns, insect bites or stings, poison ivy, poison oak, poison sumac, and minor cuts and
scratches. Pramocaine and dibucaine are also common ingredients in over the counter hemorrhoid preparations.

 

Pramoxine Hydrochloride COA:

 

Melting range 170~174°C 171.7~173.2°C
Loss on drying ≤1.0% 0.12%
Residue on ignition ≤0.1% 0.04%
Ethanol ≤0.5% 0.061%
Carbinol ≤0.3% 0.10%
Acetone ≤0.5% Not detected
Assay 98.0%~102.0% 99.98%
Conclusion The results conforms with USP33
 

 

.Related products

 

Benzocaine CAS: 94-09-7
Lidocaine CAS: 137-58-6
Propitocaine hydrochloride CAS: 1786-81-8
Tetracaine hydrochloride CAS: 136-47-0
Procaine hydrochloride CAS: 51-05-8
Pramoxine hydrochloride CAS: 637-58-1
Tetracaine CAS: 94-24-6
Proparacaine hydrochloride CAS: 5875-06-9
PROCAINE CAS: 59-46-1
Benzocaine hydrochloride CAS: 23239-88-5
Lidocaine hydrochloride CAS: 73-78-9
Articaine hydrochloride CAS: 23964-57-0
Levobupivacaine hydrochloride CAS: 27262-48-2
Ropivacaine hydrochloride CAS: 132112-35-7
Dibucaine hydrochloride CAS: 61-12-1
Bupivacaine hydrochloride CAS: 14252-80-3
Articaine CAS: 23964-58-1

 

High Quality 99% Pain Killer USP Grade Pramoxine HCL Raw Powder CAS 637-58-1

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Shanghai Doublewin Bio-Tech Co., Ltd.

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